A simple synthesis of rutaecarpine

Citation
Sh. Lee et al., A simple synthesis of rutaecarpine, HETEROCYCLE, 55(8), 2001, pp. 1555-1559
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
55
Issue
8
Year of publication
2001
Pages
1555 - 1559
Database
ISI
SICI code
0385-5414(20010801)55:8<1555:ASSOR>2.0.ZU;2-W
Abstract
Indoloquinazoline alkaloid rutaecarpine was efficiently synthesized by empl oying 9,10,11,12-tetrahydro-4H-pyrido[2,1-b]quinazoline-4,9-dione as a key intermediate, whose 9-carbonyl group was introduced by benzylidene formatio n, followed by ozonolysis.