Autism has been divided into subtypes based on social interaction/communica
tion, developmental level, or both. The validity of subtyping systems and t
he extent to which they overlap were examined. According to this review, a
single subtyping system capable of accounting for the symptom heterogeneity
in autism has not yet been proposed; however, evidence supports the presen
ce of a three-factor continuum containing at least four subgroups. Foremost
among directions for future research is the need for comprehensive studies
in which medical screening, careful selection of measures, and longitudina
l data collection are included.