The death of a 72-year-old woman with respiratory debilitation due to bronc
hogenic carcinoma is described. She overdosed herself with probably 200 to
350 mg of zopiclone. Zopiclone, quantitated by HPLC in femoral postmortem b
lood, was found to be 1.9 mg/L (4.8 mu mol/L). This level is higher than ma
ny other zopiclone fatalities reported. We report a case where only zopiclo
ne was detected.