STUDY OF THE SOLID-STATE HYDROGEN ISOTOPE-EXCHANGE OF L-ALANINE

The solid-state reaction of isotope exchange of L-alanine (L-Ala) with spillover-hydrogen activated on a Rh(Pd)-supported catalyst was studi ed. The reactivity of the carbon atoms and the activation energies of isotope exchange of the hydrogen at the C(2) and C(3) atoms of the L-A la molecule were determined using tritium NMR. The ab initio calculati ons of the activation energy of a model reaction between the alanine m olecule and a hydroxonium cation were carried out. The mechanism and p lausible structures of the transition states of this reaction were pro posed.