Synthesis of ferrocene substituted pyrrolidine derivatives via Et2Zn catalyzed 1,3-dipolar cycloaddition reactions of azomethine ylides

Authors
Dogan, O Koyuncu, H
Citation
O. Dogan et H. Koyuncu, Synthesis of ferrocene substituted pyrrolidine derivatives via Et2Zn catalyzed 1,3-dipolar cycloaddition reactions of azomethine ylides, J ORGMET CH, 631(1-2), 2001, pp. 135-138
Citations number
27
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF ORGANOMETALLIC CHEMISTRY
ISSN journal
0022328X → ACNP
Volume
631
Issue
1-2
Year of publication
2001
Pages
135 - 138
Database
ISI
SICI code
0022-328X(20010810)631:1-2<135:SOFSPD>2.0.ZU;2-1
Abstract
Synthesis of ferrocene substituted pyrrolidine derivatives via diethylzinc catalyzed 1,3-dipolar cycloadditions of azomethine ylides is described. Azo methine ylides were generated from glycine methyl ester and ferrocenecarbox aldehyde by the 'imine tautomerization' method and trapped with dipolarophi les to give the corresponding cycloadducts in reasonable yields and high re gio- and stereoselectivity. (C) 2001 Elsevier Science B.V. All rights reser ved.