Describing the pumping heart as a pressure source

Citation
M. Danielsen et Jt. Ottesen, Describing the pumping heart as a pressure source, J THEOR BIO, 212(1), 2001, pp. 71-81
Citations number
36
Categorie Soggetti
Multidisciplinary
Journal title
JOURNAL OF THEORETICAL BIOLOGY
ISSN journal
00225193 → ACNP
Volume
212
Issue
1
Year of publication
2001
Pages
71 - 81
Database
ISI
SICI code
0022-5193(20010907)212:1<71:DTPHAA>2.0.ZU;2-X
Abstract
The pumping heart is described by a new mathematical approach which conside rs the heart as a pressure source depending on time, volume and flow. This new approach allows a separation between isovolumic (non-ejecting) and ejec ting heart properties. The computed results cover most of the features of t he human ventricle during normal and altered vascular conditions. It is sho wn that the time-varying elastance concept is disqualified as an independen t description of the heart, it follows from isovolumic heart properties and an ejection effect which consists of positive and negative effects of vent ricular blood ejection. (C) 2001 Academic Press.