The authors modeled depressive and anxiety symptom data from 1.391 particip
ants in a longitudinal study of middle-aged and older Swedish twins (M age
= 60.9 years, SD = 13.3). Although anxiety and depression were highly corre
lated, a model with distinct Anxiety and Depression factors fit the data be
tter than models with Positive and Negative Affect factors or a single Ment
al Health factor. Lack of well-being was associated with anxiety rather tha
n depression. Over two 3-year intervals, anxiety symptoms led to depressive
symptoms, but the relationship was not reciprocal. Anxiety symptoms were m
ore stable than depression. These findings provide additional support for t
he idea that anxiety symptoms may reflect a personality trait such as neuro
ticism more than do depressive symptoms and suggest that low positive affec
t may not be as specific to depression among older adults as in younger peo
ple.