Over a 5-year period, 346 helical computed tomographic (CT) studies were pe
rformed in renal transplant recipients. Helical CT proved useful in this co
ntext by depicting parenchymal, perirenal, renal sinus, pyeloureteral, and
vascular complications in great detail. CT often delineates fluid collectio
ns and their anatomic relationship to adjacent structures better than ultra
sonography (US), particularly in obese patients. T-guided puncture and drai
nage can be performed in cases in which US is deemed inadequate. CT angiogr
aphy can depict arterial diseases such as stenosis, thrombosis, arterioveno
us fistulas, aneurysms, and pseudoaneurysms in the graft artery and in the
recipient iliac arterial system, thereby obviating conventional angiography
in some cases. Helical CT with three-dimensional image reformatting allows
accurate imaging of the entire course of ureteral and periureteral disease
s (eg, hydronephrosis, ureteral leak and stricture, pyeloureteral obstructi
on). CT can be used in the confirmation and staging of malignancies of the
renal parenchyma and urothelium. It is also helpful in evaluating associate
d disease in the native kidneys, acute and chronic rejection, graft emboliz
ation, and end-stage disease. Although US and nuclear medicine examination
are the imaging modalities of choice in renal transplantation, helical CT i
s a valuable alternative when these techniques are inconclusive.