Conjoined twins are rare and present a unique challenge to pediatric surgeo
ns and radiologists. Planning of surgical separation is aided by accurate p
reoperative imaging. Such twins are classified according to the most promin
ent site of connection: the thorax (thoracopagus), abdomen (omphalopagus),
sacrum (pygopagus), pelvis (ischiopagus), skull (craniopagus), face (cephal
opagus), or back (rachipagus). The area of fusion largely determines the im
aging modalities used. Thoracic conjunction is most common and requires car
diac assessment. Magnetic resonance imaging and computed tomography provide
excellent anatomic and bone detail, demonstrating organ position, shared v
iscera, and limited vascular anatomy. Contrast material radiography allows
evaluation of the gastrointestinal and urogenital tracts, and a shared live
r requires assessment of anatomy, vascularization, and biliary drainage. An
giography helps define specific vascular supply, which is useful in determi
ning the distribution of shared structures between the twins at surgery. Ea
ch set of conjoined twins is unique. An imaging strategy to accurately defi
ne anatomic fusion, vascular anomalies, and other associated abnormalities
is important for surgical planning and prognostic information.