Tetraphosphine/palladium-catalysed Suzuki cross-coupling with sterically hindered aryl bromides and arylboronic acids

Authors
Feuerstein, M Doucet, H Santelli, M
Citation
M. Feuerstein et al., Tetraphosphine/palladium-catalysed Suzuki cross-coupling with sterically hindered aryl bromides and arylboronic acids, TETRAHEDR L, 42(38), 2001, pp. 6667-6670
Citations number
36
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
38
Year of publication
2001
Pages
6667 - 6670
Database
ISI
SICI code
0040-4039(20010917)42:38<6667:TSCWSH>2.0.ZU;2-T
Abstract
cis,cis,cis-1,2,3,4-Tetrakis(diphenylphosphinomethyl)cyclopentane/[PdCl(C3H 5)](2) system efficiently catalyses the Suzuki cross-coupling of sterically hindered substrates. Very high turnover numbers can be obtained for the co upling of sterically hindered aryl bromides with benzeneboronic acid or for the coupling of bromobenzene with sterically hindered arylboronic acids. O n the other hand the formation of tri-ortho-substituted biaryl adducts requ ires higher catalyst loading. (C) 2001 Elsevier Science Ltd. All rights res erved.