Canine hyperadrenocorticism is one of the most common endocrinopathies in d
ogs. Diagnosis remains difficult in some cases due to factors such as the p
resence of non-adrenal illness and limitations in the tests. Differentiatio
n between the pituitary and adrenal forms is important for providing accura
te prognostic information and delineating treatment options and protocols.
This article reviews the tests available for diagnosis (screening) and diff
erentiation and evaluates their advantages and disadvantages. Recommendatio
ns for testing are made.