Today many patients with cancer have indwelling longterm central venous cat
heters. Benefits from catheter use include increased ease of administration
of either chemotherapy or other drugs. However, these patients are prone t
o a number of complications, including deep venous thrombosis (DVT) and inf
ection. Two kinds of catheter-related thrombi may develop: sleeve thrombi d
eveloping on the outside of intravenous catheters and occlusive DVT. Recent
studies have demonstrated that the prevalence of pulmonary embolism in pat
ients with arm DVT is high, and it is close to that observed in cohorts of
patients with lower-extremity DVT. Accordingly, some kind of prophylaxis se
ems to be warranted. Furthermore, patients with confirmed catheter-related
DVT should receive long-term anticoagulant therapy. Copyright (C) 2001 S. K
arger AG, Basel.