July 1, 1997 was stipulated as the day for estimating the prevalence of mul
tiple sclerosis within the city of Sao Paulo. The patients were identified
via various sources, including associated universities and magnetic resonan
ce services of the city of Sao Paulo. The area covered by the study has a p
opulation of 9,380,000, mainly white and of European origin, with a large n
umber of immigrants from Spain and Portugal. The patients were classified i
n accordance with the criteria of Poser et al. (1983), and only those with
defined multiple sclerosis were registered. The study gave a prevalence of
15.01/10(5) inhabitants, or three times the value obtained in a similar stu
dy in 1990. This increase reveals the large[number of cases encompassed by
the study, and is attributed to the use or more detailed recording methods,
improvements in diagnosis, and better conditions for treatment.