Early puberty is frequently observed in adopted children. This randomized t
rial treated 30 adopted children with early puberty and short stature with
either gonadotropin-re leasing hormone agonist (GnRHa) alone or in combinat
ion with growth hormone (GH) for 3 y. Before the start of treatment (TI) in
the trial and at discontinuation (T2) the children and their parents under
went a psychological evaluation. At the start of treatment the children did
not have increased levels of behavioural or emotional problems as assessed
by the Child Behaviour Checklist (CBCL). During treatment the CBCL scores
did not increase. Self-perception of the children appeared to be normal, an
d after 3 y a significantly higher score for acceptance by peers was observ
ed. At T1, an overestimation of future height was present in 80% of the chi
ldren and 17% of the parents. Lower family stress was observed at T1 and T2
compared with reference values. Intelligence quotient levels decreased sig
nificantly during treatment. The findings are discussed with reference to t
he reported levels of behavioural and emotional problems in adopted childre
n and the psychosocial effects of precocious puberty.
Conclusion: This psychological evaluation did not reveal any consistent abn
ormalities in adopted children with early puberty. Treatment with GnRHa wit
h or without GH did not increase emotional and behavioural problems in adop
ted children, nor was their self-perception decreased.