Additional dark G-band in the p-arm of chromosome 19 due to a paracentric inversion with a breakpoint in the pericentromeric heterochromatin

Authors
Fauth, C Bartels, I Haaf, T Speicher, MR
Citation
C. Fauth et al., Additional dark G-band in the p-arm of chromosome 19 due to a paracentric inversion with a breakpoint in the pericentromeric heterochromatin, AM J MED G, 103(2), 2001, pp. 160-162
Citations number
15
Categorie Soggetti
Molecular Biology & Genetics
Journal title
AMERICAN JOURNAL OF MEDICAL GENETICS
ISSN journal
01487299 → ACNP
Volume
103
Issue
2
Year of publication
2001
Pages
160 - 162
Database
ISI
SICI code
0148-7299(20011001)103:2<160:ADGITP>2.0.ZU;2-Y
Abstract
Paracentric inversions in chromosome 19 have rarely been described. Here we present an inv(19)(p11p13.1) with a breakpoint in the pericentromeric hete rochromatin which leads to an additional dark G-band in the p-arm of chromo some 19. The rearranged chromosome segregated in two generations of a famil y without any phenotypic effects. A detailed characterization of the inv(19 ) by molecular cytogenetic techniques is presented. (C) 2001 Wiley-Liss, In c.