OBJECTIVE: To define newness of drug technology and show associations betwe
en two measures of newness and health service utilization.
METHODS: Healthcare use and changes in severity at each office visit were a
ssessed for 1309 asthma patients from six health maintenance organizations
(HMOs) during 1992. The age of each drug product, derived by subtracting it
s Food and Drug Administration (FDA) approval date from January 1, 1992, wa
s used to construct two newness measures: the average age of all asthma dru
gs and, separately, all non-asthma drugs a patient used during the year and
the percentages of a patients asthma drugs from each of four time interval
s of asthma drug breakthroughs. Service utilization variables included all
primary care provider (PCP) visits, total prescription costs, emergency dep
artment (ED) visits, and hospitalizations.
RESULTS: Using either measure of drug newness, multivariate analyses showed
an association between greater use of newer asthma drugs and lower overall
drug costs and fewer PCP visits. A trend was found between greater use of
newer asthma drugs and fewer hospitalizations and ED visits. Newer non-asth
ma medications were associated with fewer ED visits.
CONCLUSIONS: After controlling for patient and site variables, greater use
of newer asthma drugs was associated with significantly lower drug costs an
d fewer PCP visits; associations with hospitalization rates and ED visits,
although lower, were not significant.