Streptococcus pneumoniae isolates with reduced susceptibility to ciprofloxacin in Spain: Clonal diversity and appearance of ciprofloxacin-resistant epidemic clones

Authors
Alou, L Ramirez, M Garcia-Rey, C Prieto, J de Lencastre, H
Citation
L. Alou et al., Streptococcus pneumoniae isolates with reduced susceptibility to ciprofloxacin in Spain: Clonal diversity and appearance of ciprofloxacin-resistant epidemic clones, ANTIM AG CH, 45(10), 2001, pp. 2955-2957
Citations number
20
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
45
Issue
10
Year of publication
2001
Pages
2955 - 2957
Database
ISI
SICI code
0066-4804(200110)45:10<2955:SPIWRS>2.0.ZU;2-Z
Abstract
Analysis of the pulsed-field gel electrophoretic profiles of 82 pneumococca l isolates with reduced susceptibility to ciprofloxacin (RSC) and of 90 co- occurring susceptible isolates indicates a considerable genetic diversity a mong isolates with RCS and points to a close relation between the two group s. This finding suggests that pneumococci with RCS emerge through independe nt mutational events.