We report the sequence of a human cDNA encoding a deduced 362 amino ac
id protein with six EF-hand calcium-binding motifs. The protein is a l
ikely human counterpart of the Cab45 protein recently identified in th
e 3T3-L1 mouse adipocyte cell line [Scherer et al. (1996), J. Cell Bio
l. 133, 257-268], displaying 87% aa and 83% nt identity with this sequ
ence. The mRNA for human Cab45 is detected ubiquitously in tissue Nort
hern blots.