In this study, the authors sought to review available epidemiologic studies
of cancer risk and its association with residence in a neighborhood charac
terized by industrial sites and to discuss options for future study design.
The authors attempted to identify all case-control studies published from
January 1980 through July 1997 in which investigators examined exposure res
ulting from residential proximity to an industrial site neighborhood relati
ve to an increased risk of lung, urinary tract, and lymphohematopoietic mal
ignancies. During these years, some authors reported significant associatio
ns between lung cancer risk and residential proximity to (a) smelters, (b)
complex industrial areas, and (c) other localized emission sources. There w
as some evidence that leukemia and lymphomas occurred in the neighborhoods
that contained industrial sites.