Sd. Cao et al., MILD STEREOSELECTIVE SYNTHESES OF THIOGLYCOSIDES UNDER PTC CONDITIONSAND THEIR USE AS ACTIVE AND LATENT GLYCOSYL DONORS, Tetrahedron : asymmetry, 5(11), 1994, pp. 2303-2312
Mild and stereoselective arylthio glycoside syntheses were accomplishe
d by inversion of configuration of glycosyl halides under phase transf
er catalyzed conditions. Under such conditions, aryl alpha-thiosialosi
des having electron donating and withdrawing substituents were evaluat
ed as active and latent thioglycosyl donors. A sialyl-alpha-(2-->6)-ga
lactoside was prepared in good yield using the above strategy.