Cerebral and cerebellar masses occured in patients with paracoccidioid
omycosis. Correct diagnosis was delayed due to overlooking the abnorma
l lung roentgenograms and the history of previous disease in a differe
nt localization. The fungus was identified through biopsy and direct e
xamination of the samples. In two patients necropsy confirmed the diag
nosis. None of the patients responded to amphotericin B or cotrimoxazo
le. A 10 year English and Latin American literature review on neuropar
acoccidioidomycosis was performed through a MEDLINE and LILACS (Latin
American Literature Search System) data base systems.