Degradation of conjugated linoleic acid isomers in the yeast Saccharomycescerevisiae

Authors
Gurvitz, A Hamilton, B Ruis, H Hartig, A Hiltunen, JK
Citation
A. Gurvitz et al., Degradation of conjugated linoleic acid isomers in the yeast Saccharomycescerevisiae, BBA-MOL C B, 1533(2), 2001, pp. 81-85
Citations number
21
Categorie Soggetti
Biochemistry & Biophysics
Journal title
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
ISSN journal
13881981 → ACNP
Volume
1533
Issue
2
Year of publication
2001
Pages
81 - 85
Database
ISI
SICI code
1388-1981(20010928)1533:2<81:DOCLAI>2.0.ZU;2-6
Abstract
Propagation of Saccharomyces cerevisiae cells in conjugated linoleic acid ( CLA) medium resulted in activation of the transcriptional machinery that re sponds to fatty acids. Cells utilized efficiently trans-10,cis-12 CLA, but not the corresponding cis-9,trans-11 isomer, probably due to the formation of cis-3,trans-5-dienoyl-CoA intermediates that are recalcitrant to beta -o xidation. (C) 2001 Elsevier Science B.V. All rights reserved.