Bronchiolitis obliterans and other late onset non-infectious pulmonary complications in hematopoietic stem cell transplantation

Authors
Afessa, B Litzow, MR Tefferi, A
Citation
B. Afessa et al., Bronchiolitis obliterans and other late onset non-infectious pulmonary complications in hematopoietic stem cell transplantation, BONE MAR TR, 28(5), 2001, pp. 425-434
Citations number
94
Categorie Soggetti
Hematology,"Medical Research Diagnosis & Treatment
Journal title
BONE MARROW TRANSPLANTATION
ISSN journal
02683369 → ACNP
Volume
28
Issue
5
Year of publication
2001
Pages
425 - 434
Database
ISI
SICI code
0268-3369(200109)28:5<425:BOAOLO>2.0.ZU;2-#
Abstract
Pulmonary complications develop in 30-60% of hematopoietic stem cell transp lants (HSCT). The main, late onset, non-infectious complications include Br onchiolitis obliterans (BO), Bronchiolitis obliterans organizing pneumonia (BOOP), and idiopathic pneumonia syndrome (IPS). BO and BOOP occur almost e xclusively in allogeneic HSCT, and have 61% and 21% mortality rates, respec tively. BOOP responds favorably to corticosteroids. IPS has less than 15% 1 -year survival.