Efficient synthesis of benzoprostacyclins using free-radical and palladium-catalyzed tandem alkene insertion strategies

Authors
Lee, NH Larock, RC
Citation
Nh. Lee et Rc. Larock, Efficient synthesis of benzoprostacyclins using free-radical and palladium-catalyzed tandem alkene insertion strategies, B KOR CHEM, 22(8), 2001, pp. 857-866
Citations number
30
Categorie Soggetti
Chemistry
Journal title
BULLETIN OF THE KOREAN CHEMICAL SOCIETY
ISSN journal
02532964 → ACNP
Volume
22
Issue
8
Year of publication
2001
Pages
857 - 866
Database
ISI
SICI code
0253-2964(20010820)22:8<857:ESOBUF>2.0.ZU;2-Y
Abstract
Efficient syntheses of PGI(2) analogue 2a and its epimer 3 have been accomp lished. Using aryl iodide 6 as the common intermediate, either radical or p alladium-assisted tandem alkene insertion strategies have been employed for construction of the benzoprostacyclin framework.