Detection of a novel t(6;15) (q21;q21) in a pediatric Wilms tumor

Authors
Fernandez, CV Lestou, VS Wildish, J Lee, CLY Sorensen, PHB
Citation
Cv. Fernandez et al., Detection of a novel t(6;15) (q21;q21) in a pediatric Wilms tumor, CANC GENET, 129(2), 2001, pp. 165-167
Citations number
21
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
CANCER GENETICS AND CYTOGENETICS
ISSN journal
01654608 → ACNP
Volume
129
Issue
2
Year of publication
2001
Pages
165 - 167
Database
ISI
SICI code
0165-4608(200109)129:2<165:DOANT(>2.0.ZU;2-8
Abstract
We report a novel cytogenetic finding in a favorable histology Wilms tumor occurring in a 4-month-old boy. Karyotypic analysis demonstrated a t(6;15)( q21;q21) in all tumor cells examined. This was confirmed using fluorescence in situ hybridization analysis. Molecular analysis of this rearrangement m ay provide clues to understanding the pathobiology of Wilms tumor. (C) 2001 Elsevier Science Inc. All rights reserved.