M. Wada et al., ACCELERATING EFFECT OF CHITOSAN INTAKE ON URINARY CALCIUM EXCRETION BY RATS, Bioscience, biotechnology, and biochemistry, 61(7), 1997, pp. 1206-1208
The effect of chitosan on calcium (Ca-47) metabolism was investigated
in rats, The whole-body retention of Ca-45 by rats fed on a 5% chitosa
n diet was significantly decreased when compared with that of rats fed
an a cellulose diet, but showed no significant difference from that o
f rats fed on a fiber-free diet. Although there was no significant dif
ference in the fecal excretion of Ca-47 between the chitosan group and
the cellulose or fiber-free group, the urinary excretion of Ca-47 was
significantly increased in the chitosan group when compared with the
cellulose group, These results suggest that dietary chitosan would aff
ect the calcium metabolism in animals.