Thrombocytopenia following eptifibatide therapy is a rare event, and acute
severe thrombocytopenia following readministration has not been reported. W
e describe a case of acute severe thrombocytopenia following reexposure to
eptifibatide during percutaneous coronary intervention. We continue to moni
tor platelet counts at 2-4 hr and 16-24 hr following administration of any
glycoprotein llb/llla inhibitor. (C) 2001 Wiley-Liss, Inc.