An unusual late relapse

We report a case of a 40-year-old man with a stage 4, anaplastic, large-cel l lymphoma. He had been diagnosed 13 years before as having a liposarcoma, at which point he was treated with combination chemotherapy, which included anthracycline. On review of the histopathology from 13 years before, the o riginal diagnosis of liposarcoma was revised to that of an anaplastic large -cell lymphoma. A diagnosis of relapsed anaplastic large-cell lymphoma was made. A MUGA scan showed a reduced ejection fraction of 46%. Our patient re sponded initially to combination chemotherapy, which included anthracycline , without further reduction in his ejection fraction. This was followed by high-dose chemotherapy and peripheral blood stem-cell transplantation. Twen ty months later he is well and remains in complete remission.