Epistaxis can be particularly difficult to treat when a patient has a coagu
lopathy, even if the area bleeding is visible. Where routine measures fail
to arrest the bleeding (e.g., nasal cautery and packing), the application o
f fibrin glue is successful in stopping the bleeding without having to addr
ess the underlying coagulopathy. Ten patients with epistaxis secondary to a
n underlying coagulopathy were treated by local application of fibrin glue
to the area bleeding. The bleeding stopped immediately in all patients when
the fibrin glue was applied. No patients suffered complications. Fibrin gl
ue application should be considered as a cost-effective means of controllin
g epistaxis from an identifiable area in the nasal cavity in patients with
a coagulopathy.