Results from physiologic studies demonstrating better tidal volume delivery
and blood gas exchange but reduced blood pressure fluctuations, and sugges
ted use of patient-triggered ventilation (PTV) rather than conventional mec
hanical ventilation, might reduce chronic lung disease and intracerebral he
morrhage. Metaanalysis of randomized trials, however, has demonstrated PTV
is only significantly associated with a shorter duration of ventilation. Th
e benefits of PTV seen in physiologic studies were largely dependent on pro
moting synchronized ventilation, but no attempt was made in any of the rand
omized trials to assess whether this occurred. To determine the efficacy of
PTV, the optimum triggering device and triggered mode, which may be diseas
e-specific, should be tested.