Channelopathies: Kir2.1 mutations jeopardize many cell functions

Authors
Jongsma, HJ Wilders, R
Citation
Hj. Jongsma et R. Wilders, Channelopathies: Kir2.1 mutations jeopardize many cell functions, CURR BIOL, 11(18), 2001, pp. R747-R750
Citations number
14
Categorie Soggetti
Experimental Biology
Journal title
CURRENT BIOLOGY
ISSN journal
09609822 → ACNP
Volume
11
Issue
18
Year of publication
2001
Pages
R747 - R750
Database
ISI
SICI code
0960-9822(20010918)11:18<R747:CKMJMC>2.0.ZU;2-T
Abstract
Andersen's syndrome is caused by mutations in the potassium channel Kir2.1, a major determinant of resting membrane potential. The clinical features o f this disease illustrate the importance of a stable resting membrane poten tial for many cell functions.