An octyl-2-cyanoacrylate formulation speeds healing of partial-thickness wounds

Background. Occlusive dressings have been known to accelerate the rate of h ealing. Every year new dressings are being introduced in the marketplace. Objective. The purpose of this study was to evaluate the effect of a new oc tyl-2-cyanoacrylate liquid dressing as compared to two over-the-counter ban dages on partial-thickness wounds. Performance parameters were epithelializ ation, erythema, scab formation, material adherence, hemostasis, and infect ion. Method. Eight pigs with a total of 645 partial-thickness wounds were assign ed to one of the following treatments: liquid dressing, standard bandage, h ydrocolloid bandage, or untreated air exposed. Result. The liquid bandage enhanced the rate of epithelialization and was t he only treatment to provide complete hemostasis, reduced scab formation, a nd did not induce an irritant response (erythema) or infection. Conclusion The liquid bandage is an easy to use material that stops bleedin g (instantaneous hemostasis) while enhancing healing of partial-thickness w ounds.