Prostatitis is a common condition that accounts for a significant number of
visits to both the emergency department and the urologist. The precise pat
hogenic mechanism of prostatitis is not known. The most prevalent theory is
that reflux of urine from the urethra into the intraprostatic ducts promot
es ascending infection and leads to chemical or bacterial prostatitis. Trea
tment is challenging because many antimicrobial agents do not effectively d
iffuse into prostatic tissue and many cases of prostatitis are not found to
have an infectious etiology. Prostatitis can be divided into different cla
ssifications which range from acute severe infections, to chronic indolent
infections, to chronic pain syndromes. The differentiation and management o
f these entities can be difficult. This article seeks to clarify the differ
ent infections, and provide a rational approach to treatment and dispositio
n of these patients.