An unusual case of endobronchial polyposis associated with extensive bronch
iectasis in the context of cystic fibrosis (CF) has been described.
A 15-yr-old female patient with CF underwent partial pneumonectomy for exte
nsive bronchiectasis and frequent infective pulmonary exacerbations.
Cylindrical bronchiectasis with associated purulent bronchitis and bronchio
litis, together with inflammatory polyposis, was noted in the resected lung
.
To the best of the authors' knowledge, this is the first report of multiple
endobronchial polyposis and may represent a rare complication of bronchiec
tasis in a patient with cystic fibrosis. On-going infection and the cellula
r composition of the polyps are discussed in relation to their possible aet
iological relevance and relationship to upper respiratory tract polyps.