Synoviorthesis with radioactive Yttrium in haemophilia: Israel experience

Radioactive Yttrium-90 (Y-90) was injected into 163 joints. Of these patien ts 115 were persons with haemophilia and they suffered from recurrent haema rthroses. The median age at the time of the initial exposure to 90Y was bet ween 11 and 15 years and the median follow-up period 11 years. Over 80% of the patients with haemophilia reported a decrease in the number of haemarth roses and 15% stopped bleeding altogether in the treated articulation. The safety of this modality of management has been reported and hence the patie nts age should not be regarded as a criteria.