Deep sclerectomy with collagen implant in patients with glaucoma and high myopia

Purpose: To study prospectively the success rate and complications of deep sclerectomy with collagen implant (DSCI), a nonpenetrating filtration proce dure, in patients with glaucoma and high myopia. Setting. Glaucoma Unit, Hopital Ophtalmique Jules Gonin, Lausanne, Switzerl and. Methods: This nonrandomized prospective trial comprised 21 eyes of 21 highl y myopic patients with medically uncontrolled primary or secondary open-ang le glaucoma. Visual acuity, intraocular pressure (IOP), and slitlamp examin ations were performed before as well as 1 and 7 days and 1, 3, 6, 9, 12, 18 , 24, 30, 36, 42, 48, 54, 60, and 66 months postoperatively. Visual field e xaminations were repeated every 6 months. Exclusion criteria were known all ergy to collagen, advanced lens opacity, and eye surgery or laser trabeculo plasty fewer than 6 months before enrollment. Results: The mean follow-up was 44.0 months +/- 17.1 (SD). The mean preoper ative IOP of 26.4 +/- 5.9 mm Hg dropped to 10.4 +/- 6.1 mm Hg at 48 months. Eighty-one percent of patients achieved an IOP below 21 mm Hg with or with out medication at 48 months. Thirty-eight percent had an IOP below 21 mm Hg without medication. The mean number of medications per patient was reduced from 2.30 +/- 0.85 to 0.86 +/- 0.91. Conclusions: Deep sclerectomy with collagen implant provided reasonable con trol of IOP in patients with glaucoma and high myopia over a long-term foll ow-up. There were relatively few postoperative complications.