E. Kaskavelis et al., Statistical analysis of catalyst degradation in a semi-continuous chemicalproduction process, J CHEMOMETR, 15(8), 2001, pp. 665-683
The effect of decaying catalyst efficacy in a commercial-scale, semi-contin
uous petrochemical process was investigated. The objective was to gain a be
tter understanding of process behaviour and its effect on production rate.
The process includes a three-stage reaction performed in fixed bed reactors
. Each of the three reaction stages consists of a number of catalyst beds t
hat are changed periodically to regenerate the catalyst. Product separation
and reactant recycling are then performed in a series of distillation colu
mns. In the absence of specific measurements of the catalyst properties, pr
ocess operational data are used to assess catalyst decay. A number of stati
stical techniques were used to model production rate as a function of proce
ss operation, including information on short- and long-term catalyst decay.
It was found that ridge regression, partial least squares and stepwise sel
ection multiple linear regression yielded similar predictive models. No add
itional benefit was found from the application of non-linear partial least
squares or Curds and Whey. Finally, through time series profiles of total d
aily production volume, corresponding to individual in-service cycles of th
e different reaction stages, short-term catalyst degradation was assessed.
It was shown that by successively modelling the process as a sequence of ba
tches corresponding to cycles of each reaction stage, considerable economic
benefit could be realized by reducing the maximum cycle length in the thir
d reaction stage. Copyright (C) 2001 John Wiley & Sons, Ltd.