Handedness preference was assessed in 205 boys with gender identity disorde
r and 205 clinical control boys referred for other reasons. Boys with gende
r identity disorder were significantly more likely to be left-handed than t
he clinical control boys (19.5 % vs. 8.3 %, respectively). The boys with ge
nder identity disorder, but not the clinical control boys, also had a signi
ficantly higher rate of left-handedness compared to three independent, gene
ral population studies of nonreferred boys (11.8 %; N = 14,253) by Hardyck,
Goldman, and Petrinovich (1975), Calnan and Richardson (1976), and Eaton,
Chipper-field, Ritchot, and Kostiuk (1996). Left-handedness appears to be a
behavioral marker of an underlying neurobiological process associated with
gender identity disorder in boys.