BENIGN SINUS HISTIOCYTOSIS - REPORT OF A CASE

A case of benign sinus histiocytosis in a three-year-old girl is repor ted. She was evaluated for a six-month of significant enlargement of a lymph node at the side of the neck. The node was firm in consistency and nontender, with no inflammatory changes, but was responsible for v enous compression and Horner's syndrome. Laboratory tests showed leuko cytosis with predominance of neutrophils, elevation of the erythrocyte sedimentation rate, and hypergammaglobulinemia. The tuberculin skin t est was negative and the chest film was normal. Histologic examination of the lymphadenopathy showed a histiocytic proliferation with plasma cells. There was no evidence of malignant disease. The outcome was fa vorable after surgery. Sinus histiocytosis is one of the reticulohisti ocytoses, which are characterized clinically by involvement of multipl e organs and tissues and histologically by a histiocytic proliferation . The cause is unknown. The outcome is favorable, either spontaneously or after surgical excision.