Stir bar sorptive extraction applied to the determination of dicarboximidefungicides in wine

The dicarboximide fungicides vinclozolin, iprodione and procymidone were an alyzed in white wines using stir bar sorptive extraction (SBSE) in combinat ion with thermal desorption-capillary GC-MS analysis (TD-cGC-MS). The metho d was optimized using spiked water samples in a concentration range between 0.5 and 100 mug/l. Iprodione was measured as its degradation product 3,5-d ichlorophenyl hydantoin. Limits of quantification in the full scan MS mode are 0.5 mug/l for vinclozolin and procymidone and 5 mug/l for iprodione. In the ion monitoring mode, concentrations 100 times lower can be dosed. Beca use of wine matrix effects on the recoveries, quantification of the target fungicides in wine had to be carried out by standard addition. For the ther molabile iprodione, the accuracy of SBSE-TD-cGC-MS was verified using SBSE followed by liquid desorption and analysis by liquid chromatography -atmosp heric pressure chemical ionization mass spectroscopy. Procymidone and iprod ione were detected in wines in concentrations up to 65 mug/l while the high est concentration of vinclozolin detected was smaller than 3 mug/l. (C) 200 1 Elsevier Science B.V. All rights reserved.