Abdominal ultrasonography (US) is the procedure of first choice in the eval
uation of a dilated common bile duct (CBD). Dilated bile ducts and the leve
l of obstruction can be reliably demonstrated with US, but the cause can be
determined in only two thirds of patients. The aim of this prospective stu
dy was to assess the value of endoscopic ultrasonography (BUS) in detecting
the cause of CBD dilatation in patients in whom US could not demonstrate t
he cause of dilation or in whom US revealed equivocal results. This 13-mont
h study included the evaluation of 985 patients. Ninety consecutive patient
s found to have an enlarged CBD (diameter, greater than or equal to7 mm) of
unexplained origin during US examination were included in this study. All
patients were evaluated by BUS. Final diagnosis was determined by endoscopi
c retrograde cholangiopancreatography with or without sphincterotomy (n=72)
and surgical exploration (n=17). The following diagnoses, were made by BUS
: choledocholithiasis in 40 patients, benign distal stricture in 8, choledo
chal cyst in 2, and ova of Ascaris in 1. The dilatation of CBD was found by
BUS examination to be caused by a tumor in 13 cases. These included tumor
of the papilla of the Vater in six patients, distal cholangiocarcinoma in f
ive, and pancreatic head cancer in two. Endoscopic ultrasonography provided
an accurate explanation for CBD dilatation in 70 of the 76 patients (92%).
We conclude that the diagnostic strategy for cholestasis should include US
as a first choice. When the diagnosis of biliary obstruction remains proba
ble, BUS should be carried out. Endoscopic retrograde cholangiopancreatogra
phy with sphincterotomy should be reserved for therapeutic use rather than
diagnostic.