S. Nakamura et al., A solid cystic tumor of the pancreas with ossification and possible malignancy, coexisting nonfusion of the pancreatic ducts, J CLIN GAST, 33(4), 2001, pp. 333-336
We report the case of a 34-year-old woman with a solid cystic tumor (SCT) o
f the pancreas accompanied by ossification and possible malignancy, coexist
ing nonfusion of the pancreatic ducts There was a 24 x 29 x 33-mm mass with
a prominent calcified lesion in the tail of the pancreas detected by abdom
inal ultrasonography, computed tomography, and magnetic resonance imaging.
There were no distal metastases detected. Endoscopic retrograde pancreatogr
aphy revealed nonfusion of the pancreatic ducts. The resected tumor consist
ed of solid and cystic components. The tumor was not encapsulated and inclu
ded a severely ossified lesion inside. On microscopy, the tumor cells were
small, eosinophilic, and proliferated in a solid or pseudo-papillary patter
n. The tumor cells infiltrated into the surrounding normal pancreas parench
yma and invaded part of the mesentery. The immunostaining was positive for
alpha-1-antitrypsin, neuron-specific enolase, vimentin, and chromogranin A.
In the literature, only a few cases of SCT of the pancreas described ossif
ication. As far as we know, only three cases of SCT of the pancreas, which
demonstrated nonfusion of the pancreatic ducts, have been reported. Thus, S
CT of the pancreas with ossification, possible malignancy, and coexisting n
onfusion of the pancreatic ducts is extremely rare.