Breast cancer is the second most common cancer among women in India, after
cancer of the cervix uteri. Presently, 75,000 new cases occur in Indian wom
en every year. This figure must be viewed against the backdrop that the nat
ional cancer registry and the hospital-based tumor registries hardly sample
3% of the total population. Locally advanced breast cancer constitutes mor
e than 50% to 70% of patients presenting for treatment. The management of t
he patients varies according to the hospital the patient seeks treatment fr
om. In this vast country, hospitals vary from peripheral hospitals with bas
ic facilities to the specialized institutions in the metropolitan centers w
ith all specialists, medical oncologists, radiation oncologists, surgical o
ncologists, and supporting facilities. In the peripheral hospitals, the tre
atment is invariably a radical mastectomy with or without radiotherapy. In
the metropolitan areas and in specialized cancer institutions, management m
irrors international recommendations with brachiocephalic trunk or modified
radical mastectomy, radiation therapy, and chemotherapy. (C) 2001 by Ameri
can Society of Clinical Oncology.