A single orthodontic activation lasting one hour can initiate tooth movemen
t. The purpose of this study is to examine tooth movement, osteoclasts, and
root resorption in rats following several one-hour activations. Rats (n =
144) were randomly assigned to intermittent (multiple activations of 1 hr/d
ay), continuous, and sham appliances. Twelve rats were killed at 3, 5, 7, a
nd 14 days. Tooth movement, osteoclasts, osteoclast %, and root resorption
% were quantified, Continuous force moved molars mesially at days 3 and 14
(p < 0.05), but intermittent and sham did not. Intermittent and continuous
force increased osteoclast numbers at days 3, 5, and 7 (p < 0.05). Continuo
us force increased osteoclast surface on days 3 and 14 (p < 0.05). Continuo
us force increased root resorption at days 5, 7, and 14 (p < 0.05). These r
esults demonstrate that orthodontic force for one hour in 24 stimulates ost
eoclasts at compression sites but does not stimulate tooth movement or root
resorption.