Therapies acting on transcription: An overview

In the future, the role of transcriptions factors and the genetic regulatio n of their expression in asthma and COPD may be an increasingly important a spect of research, as this may be one of the critical mechanisms regulating the expression of clinical phenotype and their responsiveness to therapy. Despite recent advances in the knowledge of the pathogenesis of asthma and COPD, much more research on their molecular mechanisms are needed to aid th e logical development of new therapies for these common and important disea ses, particularly in COPD were no effective treatments currently exist.