NODULAR INTRAHEPATIC LESIONS OF LIVER DIS TOMATOSIS - EFFICACY OF PRAZIQUANTEL

Human Fasciola hepatica infection is usually discovered either early, during the acute (invasive) phase, or in the advanced phase, which is characterized by biliary complications. We report a case of liver dist omatosis with nodular intra-hepatic lesions in a 58-year-old woman. Ra diological investigations showed 3 nodular lesions in the VII segment, which were difficult to distinguish from liver metastases or liver ab scesses. distomatosis serology was positive with passive hemagglutinat ion. After a 5-day treatment with praziquantel, clinical symptoms reso lved quickly while serological tests became negative. Radiological ima ges slowly decreased to a calcified scar at 13 months. No side-effects were noted. Praziquantel, whose efficacy in the common presentations of liver distomatosis has recently been demonstrated, also seems effec tive and well tolerated in case of nodular intra-hepatic lesions.