Highly collimated synchrotron sources are the essential ingredient of novel
radiology and micro-radiology techniques for materials science. medicine a
nd biology-with contrast based on the refractive index rather than on absor
ption. We were able to implement a real-time version of such techniques. Su
ccessful test studies included thin-foil breaking and electrodeposition pro
cesses in the areas concerning materials properties. Meanwhile. extensive e
ffort was dedicated to obtain high-quality X-ray images of live specimens o
n a microscopic scale and in real time. These tests achieved a lateral reso
lution better than 2 mum and a time per image of 10 ms, with clear potentia
l for further improvements. The images revealed in great detail moving part
s of different specimens. opening the way to a wide variety of applications
in the life sciences, medicine and materials science. (C) 2001 Published b
y Elsevier Science B.V.