The Joint Structural Biology Group beam lines at the ESRF: Modern macromolecular crystallography

Authors
Mitchell, EP
Citation
Ep. Mitchell, The Joint Structural Biology Group beam lines at the ESRF: Modern macromolecular crystallography, NUCL INST A, 467, 2001, pp. 1372-1374
Citations number
2
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences","Instrumentation & Measurement
Journal title
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT
ISSN journal
01689002 → ACNP
Volume
467
Year of publication
2001
Part
2
Pages
1372 - 1374
Database
ISI
SICI code
0168-9002(20010721)467:<1372:TJSBGB>2.0.ZU;2-7
Abstract
Macromolecular crystallography has evolved considerably over the last decad e. Data sets in under an hour are now possible on high throughput beam line s leading to electron density and, possibly, initial models calculated on-s ite. There are five beam lines currently dedicated to macromolecular crysta llography: the ID14 complex and BM-14 (soon to be superseded by ID-29). The se lines handle over five hundred projects every six months and demand is i ncreasing. Automated sample handling, alignment and data management protoco ls will be required to work efficiently with this demanding load. Projects developing these themes are underway within the JSBG. (C) 2001 Elsevier Sci ence B.V. All rights reserved.