Synthesis and structure determination of some oxadiazole-2-thione and triazole-3-thione galactosides

Authors
Ahmad, R Iqbal, R Akhtar, H",Zia-ul-Haq,"Duddeck, H Stefaniak, L Sitkowski, J
Citation
R. Ahmad et al., Synthesis and structure determination of some oxadiazole-2-thione and triazole-3-thione galactosides, NUCLEOS NUC, 20(9), 2001, pp. 1671-1682
Citations number
20
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
ISSN journal
15257770 → ACNP
Volume
20
Issue
9
Year of publication
2001
Pages
1671 - 1682
Database
ISI
SICI code
1525-7770(2001)20:9<1671:SASDOS>2.0.ZU;2-5
Abstract
The syntheses of 5-pyridyl-3(beta -D-galactopyranosyl)-1,3,4-oxadiazole-2-t hiones 3a-3c and 5-pyridyl-2(beta -D-galactopyranosyl)-4-benzyl-1,2, 4-tria zole-3-thiones 6a-6c are reported. The existence of N-galactosides - not S- galactosides - was proven by IR and N-15 NMR spectroscopy. The structures o f the final products and the intermediates were elucidated by IR, H-1, C-13 and N-15 NMR spectroscopy and mass spectrometry.