The use of lymphoscintigraphy and PET in the management of head and neck melanoma

Citation
Ms. Kokoska et al., The use of lymphoscintigraphy and PET in the management of head and neck melanoma, OTO H N SUR, 125(3), 2001, pp. 213-220
Citations number
20
Categorie Soggetti
Otolaryngology
Journal title
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
ISSN journal
01945998 → ACNP
Volume
125
Issue
3
Year of publication
2001
Pages
213 - 220
Database
ISI
SICI code
0194-5998(200109)125:3<213:TUOLAP>2.0.ZU;2-A
Abstract
OBJECTIVES: Lymphoscintigraphy with sentinel node dissection and 18 fluoro- 2-deoxyglucose positron emission tomography (PET) are being used independen tly in the management of many intermediate and thick melanomas of the head and neck. We report a series of patients with melanoma of the head and neck with Breslow depths greater than 1.0 mm and clinically negative regional n odes that were evaluated prospectively with PET and lymphoscintigraphy. STUDY DESIGN AND SETTING: Between July 1, 1998 and December 30, 2000 PET sc ans were obtained preoperatively on 18 patients undergoing resection of hea d and neck melanoma. Lymphoscintigraphy and sentinel node dissection was pe rformed. Resection of the primary lesion was then carried out with adequate margins and the defects were reconstructed. RESULTS: Sentinel node(s) were found in 17/18 patients (94.4%); 5/18 (27.8% ) of cases had metastases. PET detected nodal metastasis preoperatively in 3 patients (16.7%), one of which had a positive sentinel node dissection. CONCLUSION: PET and lymphoscintigraphy offer complimentary ways of evaluati on for metastatic melanoma.